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FANCG Antibody

Product Specifications

Background

The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2) . The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group G.

NCBI Gene ID

2189

Swiss Prot

O15287

Accession Number

O15287

Host

Rabbit

Reactivity

Human

Immunogen

This FANCG antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 540-568 amino acids from the C-terminal region of human FANCG.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=57-913

Calculated Molecular Weight

69 kDa

Fragment

Rabbit Ig

Symbol

FANCG

NCBI Official Name

Fanconi anemia group G protein

NCBI Organism

Homo sapiens

Background Reference 01

Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)

Background Reference 02

Wang, C., et al. Biochemistry 49 (26) :5560-5569 (2010)

Background Reference 03

Monsees, G.M., et al. Breast Cancer Res. Treat. (2010) In press :

Background Reference 04

Lipkin, S.M., et al. Cancer Prev Res (Phila) 3 (5) :597-603 (2010)

Other Product Names

Fanconi anemia group G protein, Protein FACG, DNA repair protein XRCC9, FANCG, XRCC9

Tested Applications

WB, IHC-P

Physical Properties

Liquid

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