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IL17D Antibody

Product Specifications

Background

The protein encoded by this gene is a cytokine that shares the sequence similarity with IL17. The treatment of endothelial cells with this cytokine has been shown to stimulate the production of other cytokines including IL6, IL8 and CSF2/ GM-CSF. The increased expression of IL8 induced by this cytokine was found to be NF-kappa B-dependent.

NCBI Gene ID

53342

Swiss Prot

Q8TAD2

Accession Number

Q8TAD2

Host

Rabbit

Reactivity

Human

Immunogen

This IL17D antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 155-183 amino acids from the C-terminal region of human IL17D.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Immunology

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

22 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

IL17D

NCBI Official Name

Interleukin-17D

NCBI Organism

Homo sapiens

Background Reference 01

Davila, S., et al. Genes Immun. 11 (3) :232-238 (2010)

Background Reference 02

Fakruddin, J.M., et al. Blood 109 (5) :1841-1849 (2007)

Background Reference 03

Larousserie, F., et al. J. Immunol. 176 (10) :5890-5897 (2006)

Background Reference 04

Clark, H.F., et al. Genome Res. 13 (10) :2265-2270 (2003)

Other Product Names

Interleukin-17D, IL-17D, Interleukin-27, IL-27, IL17D, IL27

Tested Applications

WB

Protein ID

46576614

Physical Properties

Liquid

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