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UBE4A Antibody

Product Specifications

Background

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes an additional conjugation factor, E4, which is involved in multiubiquitin chain assembly.

NCBI Gene ID

9354

Swiss Prot

Q14139

Accession Number

Q14139

Host

Rabbit

Reactivity

Human

Immunogen

This UBE4A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 451-479 amino acids from the Central region of human UBE4A.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=57-907

Calculated Molecular Weight

123 kDa

Fragment

Rabbit Ig

Symbol

UBE4A

NCBI Official Name

Ubiquitin conjugation factor E4 A

NCBI Organism

Homo sapiens

Background Reference 01

Shi, D., et al. Proc. Natl. Acad. Sci. U.S.A. 106 (38) :16275-16280 (2009)

Background Reference 02

Sakiyama, T., et al. Inflamm. Bowel Dis. 14 (3) :310-317 (2008)

Background Reference 03

Yang, Y., et al. Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi 23 (6) :504-506 (2007)

Background Reference 04

Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :

Other Product Names

HGNC:12499

Tested Applications

WB, IHC-P

Physical Properties

Liquid

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