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MSX2 Antibody

Product Specifications

Background

This gene encodes a member of the muscle segment homeobox gene family. The encoded protein is a transcriptional repressor whose normal activity may establish a balance between survival and apoptosis of neural crest-derived cells required for proper craniofacial morphogenesis. The encoded protein may also have a role in promoting cell growth under certain conditions and may be an important target for the RAS signaling pathways. Mutations in this gene are associated with parietal foramina 1 and craniosynostosis type 2.

NCBI Gene ID

4488

Swiss Prot

P35548

Accession Number

P35548

Host

Rabbit

Reactivity

Human

Immunogen

This MSX2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 120-148 amino acids from the Central region of human MSX2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Neuroscience

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Chicken, Xenopus, Bovine, Mouse, Rat, Zebrafish

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

29 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

MSX2

NCBI Official Name

Homeobox protein MSX-2

NCBI Organism

Homo sapiens

Background Reference 01

Nikopensius, T., et al. Birth Defects Res. PartClin. Mol. Teratol. 88 (9) :748-756 (2010)

Background Reference 02

Satoh, K., et al. J. Gastroenterol. 45 (7) :763-770 (2010)

Background Reference 03

Doi, T., et al. J. Pediatr. Surg. 45 (6) :1187-1191 (2010)

Background Reference 04

Jagomagi, T., et al. Eur. J. Oral Sci. 118 (3) :213-220 (2010)

Other Product Names

Homeobox protein MSX-2, Homeobox protein Hox-8, MSX2, HOX8

Tested Applications

WB

Protein ID

311033429

Physical Properties

Liquid

Curated Selection

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