FBLN1 Antibody
Product Specifications
Background
Fibulin 1 is a secreted glycoprotein that becomes incorporated into a fibrillar extracellular matrix. Calcium-binding is apparently required to mediate its binding to laminin and nidogen. It mediates platelet adhesion via binding fibrinogen. Four splice variants which differ in the 3' end have been identified. Each variant encodes a different isoform, but no functional distinctions have been identified among the four variants.
NCBI Gene ID
2192
Swiss Prot
P23142
Accession Number
P23142
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This FBLN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 622-650 amino acids from the C-terminal region of human FBLN1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
77 kDa
Fragment
Rabbit Ig
Symbol
FBLN1
NCBI Official Name
Fibulin-1
NCBI Organism
Homo sapiens
Background Reference 01
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Background Reference 02
Li, C., et al. Mol. Vis. 16, 689-697 (2010) :
Background Reference 03
Wooten, E.C., et al. PLoS ONE (1), E8830 (2010) :
Background Reference 04
Argraves, W.S., et al. Histochem. Cell Biol. 132 (5) :559-565 (2009)
Other Product Names
Fibulin-1, FIBL-1, FBLN1
Tested Applications
WB, IHC-P
Protein ID
215274249
Physical Properties
Liquid
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