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HMGB3 Antibody

Product Specifications

Background

HMGB3 belongs to the high mobility group (HMG) protein superfamily. Like HMG1 (MIM 163905) and HMG2 (MIM 163906), HMGB3 contains DNA-binding HMG box domains and is classified into the HMG box subfamily. Members of the HMG box subfamily are thought to play a fundamental role in DNA replication, nucleosome assembly and transcription (Wilke et al., 1997 [PubMed 9370291]; Nemeth et al., 2006 [PubMed 16945912]) .

NCBI Gene ID

3149

Swiss Prot

O15347

Accession Number

O15347

Host

Rabbit

Reactivity

Human

Immunogen

This HMGB3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 50-79 amino acids from the Central region of human HMGB3.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine, Chicken, Mouse

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

23 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

HMGB3

NCBI Official Name

High mobility group protein B3

NCBI Organism

Homo sapiens

Background Reference 01

Nemeth, M.J., et al. Proc. Natl. Acad. Sci. U.S.A. 103 (37) :13783-13788 (2006)

Background Reference 02

Ross, M.T., et al. Nature 434 (7031) :325-337 (2005)

Background Reference 03

Vaccari, T., et al. Genomics 49 (2) :247-252 (1998)

Background Reference 04

Wilke, K., et al. Gene 198 (1-2), 269-274 (1997) :

Other Product Names

High mobility group protein B3, High mobility group protein 2a, HMG-2a, High mobility group protein 4, HMG-4, HMGB3, HMG2A, HMG4

Tested Applications

WB

Physical Properties

Liquid

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