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IL25 Antibody

Product Specifications

Background

The protein encoded by this gene is a cytokine that shares sequence similarity with interleukin 17. This cytokine can induce NF-kappaB activation, and stimulate the production of interleukin 8. Both this cytokine and interleukin 17B are ligands for the cytokine receptor IL17BR. Studies of a similar gene in mice suggest that this cytokine may be a pro-inflammatory cytokine favoring the Th2-type immune response. Alternative splicing results in multiple transcript variants.

NCBI Gene ID

64806

Swiss Prot

Q9H293

Accession Number

Q9H293

Host

Rabbit

Reactivity

Human

Immunogen

This IL25 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 76-104 amino acids from the Central region of human IL25.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Immunology

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=57-895

Calculated Molecular Weight

20 kDa

Fragment

Rabbit Ig

Symbol

IL25

NCBI Official Name

Interleukin-25

NCBI Organism

Homo sapiens

Background Reference 01

Xu, G., et al. Allergy 65 (5) :581-589 (2010)

Background Reference 02

Davila, S., et al. Genes Immun. 11 (3) :232-238 (2010)

Background Reference 03

Goswami, S., et al. Nat. Immunol. 10 (5) :496-503 (2009)

Background Reference 04

Caruso, R., et al. Blood 113 (15) :3512-3519 (2009)

Other Product Names

Interleukin-25, IL-25, Interleukin-17E, IL-17E, IL25, IL17E

Tested Applications

WB, IHC-P

Protein ID

20138730

Physical Properties

Liquid

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