IL25 Antibody
Product Specifications
Background
The protein encoded by this gene is a cytokine that shares sequence similarity with interleukin 17. This cytokine can induce NF-kappaB activation, and stimulate the production of interleukin 8. Both this cytokine and interleukin 17B are ligands for the cytokine receptor IL17BR. Studies of a similar gene in mice suggest that this cytokine may be a pro-inflammatory cytokine favoring the Th2-type immune response. Alternative splicing results in multiple transcript variants.
NCBI Gene ID
64806
Swiss Prot
Q9H293
Accession Number
Q9H293
Host
Rabbit
Reactivity
Human
Immunogen
This IL25 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 76-104 amino acids from the Central region of human IL25.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Immunology
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=57-895
Calculated Molecular Weight
20 kDa
Fragment
Rabbit Ig
Symbol
IL25
NCBI Official Name
Interleukin-25
NCBI Organism
Homo sapiens
Background Reference 01
Xu, G., et al. Allergy 65 (5) :581-589 (2010)
Background Reference 02
Davila, S., et al. Genes Immun. 11 (3) :232-238 (2010)
Background Reference 03
Goswami, S., et al. Nat. Immunol. 10 (5) :496-503 (2009)
Background Reference 04
Caruso, R., et al. Blood 113 (15) :3512-3519 (2009)
Other Product Names
Interleukin-25, IL-25, Interleukin-17E, IL-17E, IL25, IL17E
Tested Applications
WB, IHC-P
Protein ID
20138730
Physical Properties
Liquid
Curated Selection
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