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BACH1 Antibody

Product Specifications

Background

This gene encodes a transcription factor that belongs to the cap'n'collar type of basic region leucine zipper factor family (CNC-bZip) . The encoded protein contains broad complex, tramtrack, bric-a-brac/poxvirus and zinc finger (BTB/POZ) domains, which is atypical of CNC-bZip family members. These BTB/POZ domains facilitate protein-protein interactions and formation of homo- and/or hetero-oligomers. When this encoded protein forms a heterodimer with MafK, it functions as a repressor of Maf recognition element (MARE) and transcription is repressed. Multiple alternatively spliced transcript variants have been identified for this gene.

NCBI Gene ID

571

Swiss Prot

O14867

Accession Number

O14867

Host

Rabbit

Reactivity

Human

Immunogen

This BACH1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 670-698 amino acids from the C-terminal region of human BACH1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

82 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

BACH1

NCBI Official Name

Transcription regulator protein BACH1

NCBI Organism

Homo sapiens

Background Reference 01

Miyazaki, T., et al. Cancer Sci. 101 (6) :1409-1416 (2010)

Background Reference 02

Hou, W., et al. Hepatology 51 (5) :1494-1504 (2010)

Background Reference 03

Gong, Z., et al. Mol. Cell 37 (3) :438-446 (2010)

Background Reference 04

Zhong, J.L., et al. Free Radic. Biol. Med. 48 (2) :196-206 (2010)

Other Product Names

Transcription regulator protein BACH1, BTB and CNC homolog 1, HA2303, BACH1

Tested Applications

WB

Physical Properties

Liquid

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