NCL Antibody
Product Specifications
Background
Nucleolin (NCL), a eukaryotic nucleolar phosphoprotein, is involved in the synthesis and maturation of ribosomes. It is located mainly in dense fibrillar regions of the nucleolus. Human NCL gene consists of 14 exons with 13 introns and spans approximately 11kb. The intron 11 of the NCL gene encodes a small nucleolar RNA, termed U20.
NCBI Gene ID
4691
Swiss Prot
P19338
Accession Number
P19338
Host
Rabbit
Reactivity
Human
Immunogen
This NCL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 276-304 amino acids from the Central region of human NCL.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Monkey
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
77 kDa
Fragment
Rabbit Ig
Symbol
NCL
NCBI Official Name
Nucleolin
NCBI Organism
Homo sapiens
Background Reference 01
Ishimaru, D., et al. J. Biol. Chem. 285 (35) :27182-27191 (2010)
Background Reference 02
Tulchin, N., et al. Am. J. Pathol. 176 (3) :1203-1214 (2010)
Background Reference 03
Strang, B.L., et al. J. Virol. 84 (4) :1771-1784 (2010)
Background Reference 04
Bertrand, L., et al. J. Virol. 84 (1) :109-118 (2010)
Other Product Names
Nucleolin, Protein C23, NCL
Tested Applications
WB, IF
Protein ID
90110781
Physical Properties
Liquid
Curated Selection
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