Mouse Dyrk1b Antibody

Product Specifications

Background

Dual-specificity kinase which possesses both serine/ threonine and tyrosine kinase activity. Enhances the transcriptional activity of TCF1/HNF1A and FOXO1. Inhibits epithelial cell migration. Mediates colon carcinoma cell survival in mitogen-poor environments.

NCBI Gene ID

13549

Swiss Prot

Q9Z188

Accession Number

Q9Z188

Host

Rabbit

Reactivity

Mouse

Immunogen

This Mouse Dyrk1b antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 376-403 amino acids from the Central region of mouse Dyrk1b.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Human

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

69 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

Dyrk1b

NCBI Official Name

Dual specificity tyrosine-phosphorylation-regulated kinase 1B

NCBI Organism

Mus musculus

Background Reference 01

Janumyan, Y., et al. J. Biol. Chem. 283 (49) :34108-34120 (2008)

Background Reference 02

Munton, R.P., et al. Mol. Cell Proteomics 6 (2) :283-293 (2007)

Background Reference 03

Mercer, S.E., et al. J. Biol. Chem. 280 (27) :25788-25801 (2005)

Background Reference 04

Collins, M.O., et al. J. Biol. Chem. 280 (7) :5972-5982 (2005)

Other Product Names

Dual specificity tyrosine-phosphorylation-regulated kinase 1B, Dyrk1b

Tested Applications

Physical Properties

Liquid

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