FST Antibody

Product Specifications

Background

Follistatin is a single-chain gonadal protein that specifically inhibits follicle-stimulating hormone release. The single FST gene encodes two isoforms, FST317 and FST344 containing 317 and 344 amino acids respectively, resulting from alternative splicing of the precursor mRNA. In a study in which 37 candidate genes were tested for linkage and association with polycystic ovary syndrome (PCOS) or hyperandrogenemia in 150 families, evidence was found for linkage between PCOS and follistatin. [provided by RefSeq].

NCBI Gene ID

10468

Swiss Prot

P19883

Accession Number

P19883

Host

Rabbit

Reactivity

Human

Immunogen

This FST antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 312-340 amino acids from the C-terminal region of human FST.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine, Chicken, Pig

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

38 kDa

Fragment

Rabbit Ig

Symbol

FST

NCBI Official Name

Follistatin

NCBI Organism

Homo sapiens

Background Reference 01

Chen, M.J., et al. Hum. Reprod. 25 (3) :779-785 (2010)

Background Reference 02

Jugessur, A., et al. PLoS ONE (7), E11493 (2010) :

Background Reference 03

Johnatty, S.E., et al. PLoS Genet. (7), E1001016 (2010) :

Background Reference 04

Fajardo, M., et al. Clin. Orthop. Relat. Res. 467 (12) :3071-3078 (2009)

Other Product Names

Follistatin, FS, Activin-binding protein, FST

Tested Applications

WB, IHC-P

Protein ID

23831079

Physical Properties

Liquid

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