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P2RY1 Antibody

Product Specifications

Background

The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor functions as a receptor for extracellular ATP and ADP. In platelets binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C, a change in platelet shape, and probably to platelet aggregation. [provided by RefSeq].

NCBI Gene ID

5028

Swiss Prot

P47900

Accession Number

P47900

Host

Rabbit

Reactivity

Human

Immunogen

This P2RY1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 231-260 amino acids from the Central region of human P2RY1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience, Signal Transduction, Growth Factors

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine, Chicken, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

42 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

P2RY1

NCBI Official Name

P2Y purinoceptor 1

NCBI Organism

Homo sapiens

Background Reference 01

Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)

Background Reference 02

Maloney, S.F., et al. Integr Biol (Camb) 2 (4) :183-192 (2010)

Background Reference 03

Nisar, S., et al. Traffic 11 (4) :508-519 (2010)

Background Reference 04

Kumar, T.S., et al. J. Med. Chem. 53 (6) :2562-2576 (2010)

Other Product Names

P2Y purinoceptor 1, P2Y1, ATP receptor, Purinergic receptor, P2RY1

Tested Applications

WB

Protein ID

1352692

Physical Properties

Liquid

Frequently Asked Questions

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