PAEP Antibody
Product Specifications
Background
This gene is a member of the kernel lipocalin superfamily whose members share relatively low sequence similarity but have highly conserved exon/intron structure and three-dimensional protein folding. Most lipocalins are clustered on the long arm of chromosome 9. The encoded glycoprotein has been previously referred to as pregnancy-associated endometrial alpha-2-globulin, placental protein 14, and glycodelin, but has been officially named progestagen-associated endometrial protein. Three distinct forms, with identical protein backbones but different glycosylation profiles, are found in amniotic fluid, follicular fluid and seminal plasma of the reproductive system. These glycoproteins have distinct and essential roles in regulating a uterine environment suitable for pregnancy and in the timing and occurrence of the appropriate sequence of events in the fertilization process. A number of alternatively spliced transcript variants have been observed at this locus, but the full-length nature of only two, each encoding the same protein, has been determined. [provided by RefSeq].
NCBI Gene ID
5047
Swiss Prot
P09466
Accession Number
P09466
Host
Rabbit
Reactivity
Human
Immunogen
This PAEP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 73-101 amino acids from the Central region of human PAEP.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=57-832
Calculated Molecular Weight
21 kDa
Fragment
Rabbit Ig
Symbol
PAEP
NCBI Official Name
Glycodelin
NCBI Organism
Homo sapiens
Background Reference 01
Soni, C., et al. Mol. Immunol. 47 (15) :2458-2466 (2010)
Background Reference 02
Lee, C.L., et al. Fertil. Steril. 94 (2) :769-771 (2010)
Background Reference 03
Tsviliana, A., et al. Anticancer Res. 30 (5) :1637-1640 (2010)
Background Reference 04
Scholz, C., et al. Anticancer Res. 30 (5) :1599-1603 (2010)
Other Product Names
Glycodelin, GD, Placental protein 14, PP14, Pregnancy-associated endometrial alpha-2 globulin, PAEG, PEG, Progestagen-associated endometrial protein, Progesterone-associated endometrial protein, PAEP
Tested Applications
WB, IHC-P
Protein ID
130701
Physical Properties
Liquid
Curated Selection
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