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PAEP Antibody

Product Specifications

Background

This gene is a member of the kernel lipocalin superfamily whose members share relatively low sequence similarity but have highly conserved exon/intron structure and three-dimensional protein folding. Most lipocalins are clustered on the long arm of chromosome 9. The encoded glycoprotein has been previously referred to as pregnancy-associated endometrial alpha-2-globulin, placental protein 14, and glycodelin, but has been officially named progestagen-associated endometrial protein. Three distinct forms, with identical protein backbones but different glycosylation profiles, are found in amniotic fluid, follicular fluid and seminal plasma of the reproductive system. These glycoproteins have distinct and essential roles in regulating a uterine environment suitable for pregnancy and in the timing and occurrence of the appropriate sequence of events in the fertilization process. A number of alternatively spliced transcript variants have been observed at this locus, but the full-length nature of only two, each encoding the same protein, has been determined. [provided by RefSeq].

NCBI Gene ID

5047

Swiss Prot

P09466

Accession Number

P09466

Host

Rabbit

Reactivity

Human

Immunogen

This PAEP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 73-101 amino acids from the Central region of human PAEP.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=57-832

Calculated Molecular Weight

21 kDa

Fragment

Rabbit Ig

Symbol

PAEP

NCBI Official Name

Glycodelin

NCBI Organism

Homo sapiens

Background Reference 01

Soni, C., et al. Mol. Immunol. 47 (15) :2458-2466 (2010)

Background Reference 02

Lee, C.L., et al. Fertil. Steril. 94 (2) :769-771 (2010)

Background Reference 03

Tsviliana, A., et al. Anticancer Res. 30 (5) :1637-1640 (2010)

Background Reference 04

Scholz, C., et al. Anticancer Res. 30 (5) :1599-1603 (2010)

Other Product Names

Glycodelin, GD, Placental protein 14, PP14, Pregnancy-associated endometrial alpha-2 globulin, PAEG, PEG, Progestagen-associated endometrial protein, Progesterone-associated endometrial protein, PAEP

Tested Applications

WB, IHC-P

Protein ID

130701

Physical Properties

Liquid

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