WIF1 Antibody
Product Specifications
Background
The protein encoded by this gene functions to inhibit WNT proteins, which are extracellular signaling molecules that play a role in embryonic development. This protein contains a WNT inhibitory factor (WIF) domain and five epidermal growth factor (EGF) -like domains, and is thought to be involved in mesoderm segmentation. This gene functions as a tumor suppressor gene, and has been found to be epigenetically silenced in various cancers.
NCBI Gene ID
11197
Swiss Prot
Q9Y5W5
Accession Number
Q9Y5W5
Host
Rabbit
Reactivity
Human
Immunogen
This WIF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 344-373 amino acids from the C-terminal region of human WIF1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
42 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
WIF1
NCBI Official Name
Wnt inhibitory factor 1
NCBI Organism
Homo sapiens
Background Reference 01
Licchesi, J.D., et al. Oncogene 29 (44) :5923-5934 (2010)
Background Reference 02
Fendri, A., et al. Cancer Invest. 28 (9) :896-903 (2010)
Background Reference 03
Kohno, H., et al. Oncol. Rep. 24 (2) :423-431 (2010)
Background Reference 04
Belshaw, N.J., et al. Carcinogenesis 31 (6) :1158-1163 (2010)
Other Product Names
Wnt inhibitory factor 1, WIF-1, WIF1
Tested Applications
WB
Protein ID
61252765
Physical Properties
Liquid
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