KLK10 Antibody

Product Specifications

Background

Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its encoded protein is secreted and may play a role in suppression of tumorigenesis in breast and prostate cancers. Alternate splicing of this gene results in multiple transcript variants encoding the same protein. [provided by RefSeq].

NCBI Gene ID

5655

Swiss Prot

O43240

Accession Number

O43240

Host

Rabbit

Reactivity

Human

Immunogen

This KLK10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 22-51 amino acids from the N-terminal region of human KLK10.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Cell Cycle, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

30 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

KLK10

NCBI Official Name

Kallikrein-10

NCBI Organism

Homo sapiens

Background Reference 01

Batra, J., et al. Int. J. Gynecol. Cancer 20 (4) :529-536 (2010)

Background Reference 02

Klein, R.J., et al. Cancer Prev Res (Phila) 3 (5) :611-619 (2010)

Background Reference 03

Papageorgis, P., et al. Cancer Res. 70 (3) :968-978 (2010)

Background Reference 04

Lu, C.Y., et al. Genes Chromosomes Cancer 48 (12) :1057-1068 (2009)

Other Product Names

Kallikrein-10, 3421-, Normal epithelial cell-specific 1, Protease serine-like 1, KLK10, NES1, PRSSL1

Tested Applications

Physical Properties

Liquid

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

MBS189545-01 0.01 mg

Human GPR132 Protein, hFc Tag

Ask

View Details

MBS189545-02 0.05 mg

Human GPR132 Protein, hFc Tag

Ask

View Details

MBS189545-03 0.1 mg

Human GPR132 Protein, hFc Tag

Ask

View Details

MBS189545-04 5x 0.1 mg

Human GPR132 Protein, hFc Tag

Ask

View Details

ant-730 5µg

HA-tag Peptide PAT5E7AT

Ask

View Details

E51A12759 100 µL

KLHL2 Antibody

Ask

View Details