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SOCS4 Antibody

Product Specifications

Background

The protein encoded by this gene contains a SH2 domain and a SOCS BOX domain. The protein thus belongs to the suppressor of cytokine signaling (SOCS), also known as STAT-induced STAT inhibitor (SSI), protein family. SOCS family members are known to be cytokine-inducible negative regulators of cytokine signaling. Two alternatively spliced transcript variants encoding the same protein have been found for this gene.

NCBI Gene ID

122809

Swiss Prot

Q8WXH5

Accession Number

Q8WXH5

Host

Rabbit

Reactivity

Human

Immunogen

This SOCS4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 224-253 amino acids from the Central region of human SOCS4.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

51 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

SOCS4

NCBI Official Name

Suppressor of cytokine signaling 4

NCBI Organism

Homo sapiens

Background Reference 01

Hu, G., et al. J. Infect. Dis. 202 (1) :125-135 (2010)

Background Reference 02

Han, S., et al. Hum. Immunol. 71 (7) :727-730 (2010)

Background Reference 03

Rajaraman, P., et al. Cancer Epidemiol. Biomarkers Prev. 19 (5) :1356-1361 (2010)

Background Reference 04

Sasi, W., et al. BMC Cancer 10, 178 (2010) :

Other Product Names

Suppressor of cytokine signaling 4, SOCS-4, Suppressor of cytokine signaling 7, SOCS-7, SOCS4, SOCS7

Tested Applications

WB

Protein ID

20178106

Physical Properties

Liquid

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