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ARC Antibody

Product Specifications

Background

ARCis required for consolidation of synaptic plasticity as well as formation of long-term memory. Regulates endocytosis of AMPA receptors in response to synaptic activity. Required for homeostatic synaptic scaling of AMPA receptors (By similarity) .

NCBI Gene ID

23237

Swiss Prot

Q7LC44

Accession Number

Q7LC44

Host

Rabbit

Reactivity

Human

Immunogen

This ARC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 37-66 amino acids from the N-terminal region of human ARC.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

45 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

ARC

NCBI Official Name

Activity-regulated cytoskeleton-associated protein

NCBI Organism

Homo sapiens

Background Reference 01

Bloomer, W.A., et al. Brain Res. 1153, 20-33 (2007) :

Background Reference 02

Dynes, J.L., et al. J. Comp. Neurol. 500 (3) :433-447 (2007)

Background Reference 03

Haug, K., et al. Mol. Cell. Probes 14 (4) :255-260 (2000)

Background Reference 04

Kremerskothen, J., et al. Chromosome Res. (7), 655 (2000) :

Other Product Names

Activity-regulated cytoskeleton-associated protein, ARC/ARG31, Activity-regulated gene 31 protein homolog, Arg31, ARC {ECO:0000312|EMBL:AAG337051}

Tested Applications

WB

Protein ID

74738627

Physical Properties

Liquid

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