PRPF31 Antibody

Product Specifications

Background

This gene encodes a component of the spliceosome complex and is one of several retinitis pigmentosa-causing genes. When the gene product is added to the spliceosome complex, activation occurs.

NCBI Gene ID

26121

Swiss Prot

Q8WWY3

Accession Number

Q8WWY3

Host

Rabbit

Reactivity

Human

Immunogen

This PRPF31 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 334-361 amino acids from the C-terminal region of human PRPF31.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Zebrafish, Mouse, Xenopus

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

55 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

PRPF31

NCBI Official Name

U4/U6 small nuclear ribonucleoprotein Prp31

NCBI Organism

Homo sapiens

Background Reference 01

Schneider, M., et al. Nat. Struct. Mol. Biol. 17 (2) :216-221 (2010)

Background Reference 02

Bujakowska, K., et al. Invest. Ophthalmol. Vis. Sci. 50 (12) :5927-5933 (2009)

Background Reference 03

Potkin, S.G., et al. PLoS ONE (8), E6501 (2009) :

Background Reference 04

Liu, S., et al. Science 316 (5821) :115-120 (2007)

Other Product Names

U4/U6 small nuclear ribonucleoprotein Prp31, Pre-mRNA-processing factor 31, Serologically defined breast cancer antigen NY-BR-99, U4/U6 snRNP 61 kDa protein, Protein 61K, hPrp31, PRPF31, PRP31