WASF2 Antibody

Product Specifications

Background

This gene encodes a member of the Wiskott-Aldrich syndrome protein family. The gene product is a protein that forms a multiprotein complex that links receptor kinases and actin. Binding to actin occurs through a C-terminal verprolin homology domain in all family members. The multiprotein complex serves to tranduce signals that involve changes in cell shape, motility or function. The published map location (PMID:10381382) has been changed based on recent genomic sequence comparisons, which indicate that the expressed gene is located on chromosome 1, and a pseudogene may be located on chromosome X.

NCBI Gene ID

10163

Swiss Prot

Q9Y6W5

Accession Number

Q9Y6W5

Host

Rabbit

Reactivity

Human

Immunogen

This WASF2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 162-190 amino acids from the Central region of human WASF2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine, Mouse

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

54 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

WASF2

NCBI Official Name

Wiskott-Aldrich syndrome protein family member 2

NCBI Organism

Homo sapiens

Background Reference 01

Takahashi, K., et al. Cell. Signal. 22 (3) :510-518 (2010)

Background Reference 02

Lebensohn, A.M., et al. Mol. Cell 36 (3) :512-524 (2009)

Background Reference 03

Cai, X., et al. Lung Cancer 65 (3) :299-305 (2009)

Background Reference 04

Morimura, S., et al. Biochem. Biophys. Res. Commun. 382 (3) :614-619 (2009)

Other Product Names

Wiskott-Aldrich syndrome protein family member 2, WASP family protein member 2, Protein WAVE-2, Verprolin homology domain-containing protein 2, WASF2, WAVE2