TAF9B Antibody
Product Specifications
Background
Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes a protein that is similar to one of the small subunits of TFIID, TBP-associated factor 9, and is also a subunit of TFIID. TAF9 and TAF9b share some functions but also have distinct roles in the transcriptional regulatory process.
NCBI Gene ID
51616
Swiss Prot
Q9HBM6
Accession Number
Q9HBM6
Host
Rabbit
Reactivity
Human
Immunogen
This TAF9B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 44-72 amino acids from the N-terminal region of human TAF9B.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
28 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
TAF9B
NCBI Official Name
Transcription initiation factor TFIID subunit 9B
NCBI Organism
Homo sapiens
Background Reference 01
Frontini, M., et al. Mol. Cell. Biol. 25 (11) :4638-4649 (2005)
Background Reference 02
Ross, M.T., et al. Nature 434 (7031) :325-337 (2005)
Background Reference 03
Chen, Z., et al. J. Biol. Chem. 278 (37) :35172-35183 (2003)
Background Reference 04
Albright, S.R., et al. Gene 242 (1-2), 1-13 (2000) :
Other Product Names
Transcription initiation factor TFIID subunit 9B, Neuronal cell death-related protein 7, DN-7, Transcription initiation factor TFIID subunit 9-like, Transcription-associated factor TAFII31L, TAF9B, TAF9L
Tested Applications
WB
Protein ID
74752778
Physical Properties
Liquid
Curated Selection
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