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TAF9B Antibody

Product Specifications

Background

Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes a protein that is similar to one of the small subunits of TFIID, TBP-associated factor 9, and is also a subunit of TFIID. TAF9 and TAF9b share some functions but also have distinct roles in the transcriptional regulatory process.

NCBI Gene ID

51616

Swiss Prot

Q9HBM6

Accession Number

Q9HBM6

Host

Rabbit

Reactivity

Human

Immunogen

This TAF9B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 44-72 amino acids from the N-terminal region of human TAF9B.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

28 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

TAF9B

NCBI Official Name

Transcription initiation factor TFIID subunit 9B

NCBI Organism

Homo sapiens

Background Reference 01

Frontini, M., et al. Mol. Cell. Biol. 25 (11) :4638-4649 (2005)

Background Reference 02

Ross, M.T., et al. Nature 434 (7031) :325-337 (2005)

Background Reference 03

Chen, Z., et al. J. Biol. Chem. 278 (37) :35172-35183 (2003)

Background Reference 04

Albright, S.R., et al. Gene 242 (1-2), 1-13 (2000) :

Other Product Names

Transcription initiation factor TFIID subunit 9B, Neuronal cell death-related protein 7, DN-7, Transcription initiation factor TFIID subunit 9-like, Transcription-associated factor TAFII31L, TAF9B, TAF9L

Tested Applications

WB

Protein ID

74752778

Physical Properties

Liquid

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