SEC23IP Antibody
Product Specifications
Background
COPII-coated vesicles are involved in protein transport from the endoplasmic reticulum to the Golgi apparatus. The protein encoded by this gene was identified by its interaction with a mouse protein similar to yeast Sec23p, an essential component of the COPII. This protein shares significant similarity with phospholipid-modifying proteins, especially phosphatidic acid preferring-phospholipase A1. Overexpression of this protein has been shown to cause disorganization of the endoplasmic reticulum-Golgi intermediate compartment and Golgi apparatus, which suggests its role in the early secretory pathway. [provided by RefSeq].
NCBI Gene ID
11196
Swiss Prot
Q9Y6Y8
Accession Number
Q9Y6Y8
Host
Rabbit
Reactivity
Human
Immunogen
This SEC23IP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 724-752 amino acids from the C-terminal region of human SEC23IP.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
111 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
SEC23IP
NCBI Official Name
SEC23-interacting protein
NCBI Organism
Homo sapiens
Background Reference 01
Ong, Y.S., et al. J. Cell Biol. 190 (3) :331-345 (2010)
Background Reference 02
Trynka, G., et al. Gut 58 (8) :1078-1083 (2009)
Background Reference 03
Li, H., et al. J. Biol. Chem. 281 (21) :14748-14755 (2006)
Background Reference 04
Grupe, A., et al. Am. J. Hum. Genet. 78 (1) :78-88 (2006)
Other Product Names
SEC23-interacting protein, p125, SEC23IP
Tested Applications
WB
Protein ID
55584014
Physical Properties
Liquid
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