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SEC23IP Antibody

Product Specifications

Background

COPII-coated vesicles are involved in protein transport from the endoplasmic reticulum to the Golgi apparatus. The protein encoded by this gene was identified by its interaction with a mouse protein similar to yeast Sec23p, an essential component of the COPII. This protein shares significant similarity with phospholipid-modifying proteins, especially phosphatidic acid preferring-phospholipase A1. Overexpression of this protein has been shown to cause disorganization of the endoplasmic reticulum-Golgi intermediate compartment and Golgi apparatus, which suggests its role in the early secretory pathway. [provided by RefSeq].

NCBI Gene ID

11196

Swiss Prot

Q9Y6Y8

Accession Number

Q9Y6Y8

Host

Rabbit

Reactivity

Human

Immunogen

This SEC23IP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 724-752 amino acids from the C-terminal region of human SEC23IP.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=57-779

Calculated Molecular Weight

111 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

SEC23IP

NCBI Official Name

SEC23-interacting protein

NCBI Organism

Homo sapiens

Background Reference 01

Ong, Y.S., et al. J. Cell Biol. 190 (3) :331-345 (2010)

Background Reference 02

Trynka, G., et al. Gut 58 (8) :1078-1083 (2009)

Background Reference 03

Li, H., et al. J. Biol. Chem. 281 (21) :14748-14755 (2006)

Background Reference 04

Grupe, A., et al. Am. J. Hum. Genet. 78 (1) :78-88 (2006)

Other Product Names

SEC23-interacting protein, p125, SEC23IP

Tested Applications

WB

Protein ID

55584014

Physical Properties

Liquid

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