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ASAP1 Antibody

Product Specifications

Background

Possesses phosphatidylinositol 4,5-biphosphate-dependent GTPase-activating protein activity for ARF1 (ADP ribosylation factor 1) and ARF5 and a lesser activity towards ARF6. May coordinate membrane trafficking with cell growth or actin cytoskeleton remodeling by binding to both SRC and PIP2. May function as a signal transduction protein involved in the differentiation of fibroblasts into adipocytes and possibly other cell types (By similarity) .

NCBI Gene ID

50807

Swiss Prot

Q9ULH1

Accession Number

Q9ULH1

Host

Rabbit

Reactivity

Mouse

Immunogen

This ASAP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 360-388 amino acids from the Central region of human ASAP1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=57-774

Calculated Molecular Weight

125 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

ASAP1

NCBI Official Name

Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1

NCBI Organism

Homo sapiens

Background Reference 01

Muller, T., et al. Oncogene 29 (16) :2393-2403 (2010)

Background Reference 02

Nat. Genet. 41 (7) :824-828 (2009)

Background Reference 03

Jian, X., et al. J. Biol. Chem. 284 (3) :1652-1663 (2009)

Background Reference 04

Inoue, H., et al. Mol. Biol. Cell 19 (10) :4224-4237 (2008)

Other Product Names

Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1, 130 kDa phosphatidylinositol 4,5-bisphosphate-dependent ARF1 GTPase-activating protein, ADP-ribosylation factor-directed GTPase-activating protein 1, ARF GTPase-activating protein 1, Development and differentiation-enhancing factor 1, DEF-1, Differentiation-enhancing factor 1, PIP2-dependent ARF1 GAP, ASAP1, DDEF1, KIAA1249

Tested Applications

WB

Protein ID

296439459

Physical Properties

Liquid

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