B3GALT2 Antibody
Product Specifications
Background
This gene is a member of the beta-1,3-galactosyltransferase (beta3GalT) gene family. This family encodes type II membrane-bound glycoproteins with diverse enzymatic functions using different donor substrates (UDP-galactose and UDP-N-acetylglucosamine) and different acceptor sugars (N-acetylglucosamine, galactose, N-acetylgalactosamine) . The beta3GalT genes are distantly related to the Drosophila Brainiac gene and have the protein coding sequence contained in a single exon. The beta3GalT proteins also contain conserved sequences not found in the beta4GalT or alpha3GalT proteins. The carbohydrate chains synthesized by these enzymes are designated as type 1, whereas beta4GalT enzymes synthesize type 2 carbohydrate chains. The ratio of type 1:type 2 chains changes during embryogenesis. By sequence similarity, the beta3GalT genes fall into at least two groups: beta3GalT4 and 4 other beta3GalT genes (beta3GalT1-3, beta3GalT5) . This gene encodes a protein that functions in N-linked glycoprotein glycosylation and shows strict donor substrate specificity for UDP-galactose.
NCBI Gene ID
8707
Swiss Prot
O43825
Accession Number
O43825
Host
Rabbit
Reactivity
Mouse
Immunogen
This B3GALT2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 394-422 amino acids from the C-terminal region of human B3GALT2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
49 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
B3GALT2
NCBI Official Name
Beta-1,3-galactosyltransferase 2
NCBI Organism
Homo sapiens
Background Reference 01
Lamesch, P., et al. Genomics 89 (3) :307-315 (2007)
Background Reference 02
Sood, R., et al. Genomics 73 (2) :211-222 (2001)
Background Reference 03
Amado, M., et al. Biochim. Biophys. Acta 1473 (1) :35-53 (1999)
Background Reference 04
Amado, M., et al. J. Biol. Chem. 273 (21) :12770-12778 (1998)
Other Product Names
Beta-1,3-galactosyltransferase 2, Beta-1,3-GalTase 2, Beta3Gal-T2, Beta3GalT2, 241-, UDP-galactose:2-acetamido-2-deoxy-D-glucose 3beta-galactosyltransferase 2, B3GALT2
Tested Applications
WB
Physical Properties
Liquid
Curated Selection
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