Mouse Map4k4 Antibody

Product Specifications

Background

Serine/threonine kinase that may play a role in the response to environmental stress and cytokines such as TNF-alpha. Appears to act upstream of the JUN N-terminal pathway.

NCBI Gene ID

26921

Swiss Prot

P97820

Accession Number

P97820

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This Mouse Map4k4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 506-534 amino acids from the Central region of mouse Map4k4.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

141 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

Map4k4

NCBI Official Name

Mitogen-activated protein kinase kinase kinase kinase 4

NCBI Organism

Mus musculus

Background Reference 01

Maruyama, T., et al. J. Bone Miner. Res. 25 (5) :1058-1067 (2010)

Background Reference 02

Guntur, K.V., et al. J. Biol. Chem. 285 (9) :6595-6603 (2010)

Background Reference 03

Aouadi, M., et al. Nature 458 (7242) :1180-1184 (2009)

Background Reference 04

Wittwer, T., et al. Biochem. Biophys. Res. Commun. 371 (2) :294-297 (2008)

Other Product Names

Mitogen-activated protein kinase kinase kinase kinase 4, HPK/GCK-like kinase HGK, MAPK/ERK kinase kinase kinase 4, MEK kinase kinase 4, MEKKK 4, Nck-interacting kinase, Map4k4, Nik