GTF2E1 Antibody

Product Specifications

Background

Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.

NCBI Gene ID

2960

Swiss Prot

P29083

Accession Number

P29083

Host

Rabbit

Reactivity

Human

Immunogen

This GTF2E1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 93-121 amino acids from the N-terminal region of human GTF2E1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

49 kDa

Fragment

Rabbit Ig

Symbol

GTF2E1

NCBI Official Name

General transcription factor IIE subunit 1

NCBI Organism

Homo sapiens

Background Reference 01

Vega, A., et al. Gynecol. Oncol. 112 (1) :210-214 (2009)

Background Reference 02

Okuda, M., et al. EMBO J. 27 (7) :1161-1171 (2008)

Background Reference 03

Di Lello, P., et al. Proc. Natl. Acad. Sci. U.S.A. 105 (1) :106-111 (2008)

Background Reference 04

Jawhari, A., et al. EMBO Rep. 7 (5) :500-505 (2006)

Other Product Names

General transcription factor IIE subunit 1, General transcription factor IIE 56 kDa subunit, Transcription initiation factor IIE subunit alpha, TFIIE-alpha, GTF2E1, TF2E1