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PTGIR Antibody

Product Specifications

Background

The protein encoded by this gene is a member of the G-protein coupled receptor family 1 and has been shown to be a receptor for prostacyclin. Prostacyclin, the major product of cyclooxygenase in macrovascular endothelium, elicits a potent vasodilation and inhibition of platelet aggregation through binding to this receptor.

NCBI Gene ID

5739

Swiss Prot

P43119

Accession Number

P43119

Host

Rabbit

Reactivity

Human

Immunogen

This PTGIR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 210-238 amino acids from the Central region of human PTGIR.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction, Growth Factors

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

41 kDa

Fragment

Rabbit Ig

Symbol

PTGIR

NCBI Official Name

Prostacyclin receptor

NCBI Organism

Homo sapiens

Background Reference 01

Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)

Background Reference 02

Ibrahim, S., et al. Arterioscler. Thromb. Vasc. Biol. 30 (9) :1802-1809 (2010)

Background Reference 03

Reid, H.M., et al. J. Biol. Chem. 285 (24) :18709-18726 (2010)

Background Reference 04

Muto, A., et al. Int Angiol 29 (2 SUPPL), 43-48 (2010) :

Other Product Names

Prostacyclin receptor, Prostaglandin I2 receptor, PGI receptor, PGI2 receptor, Prostanoid IP receptor, PTGIR, PRIPR

Tested Applications

WB, IHC-P

Protein ID

1172500

Physical Properties

Liquid

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