ADORA1 Antibody
Product Specifications
Background
The protein encoded by this gene is an adenosine receptor that belongs to the G-protein coupled receptor 1 family. There are 3 types of adenosine receptors, each with a specific pattern of ligand binding and tissue distribution, and together they regulate a diverse set of physiologic functions. The type A1 receptors inhibit adenylyl cyclase, and play a role in the fertilization process. Animal studies also suggest a role for A1 receptors in kidney function and ethanol intoxication. Transcript variants with alternative splicing in the 5' UTR have been found for this gene.
NCBI Gene ID
134
Swiss Prot
P30542
Accession Number
P30542
Host
Rabbit
Reactivity
Human
Immunogen
This ADORA1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 298-326 amino acids from the C-terminal region of human ADORA1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Immunology, Neuroscience, Signal Transduction, Growth Factors
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
37 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
ADORA1
NCBI Official Name
Adenosine receptor A1
NCBI Organism
Homo sapiens
Background Reference 01
Lane, J.R., et al. Biochem. Pharmacol. 80 (8) :1180-1189 (2010)
Background Reference 02
Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)
Background Reference 03
Wagner, A.K., et al. Epilepsy Res. 90 (3) :259-272 (2010)
Background Reference 04
Ruano, G., et al. Pharmacogenomics 11 (7) :959-971 (2010)
Other Product Names
Adenosine receptor A1, ADORA1
Tested Applications
WB
Protein ID
231473
Physical Properties
Liquid
Frequently Asked Questions
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