ADORA1 Antibody

Product Specifications

Background

The protein encoded by this gene is an adenosine receptor that belongs to the G-protein coupled receptor 1 family. There are 3 types of adenosine receptors, each with a specific pattern of ligand binding and tissue distribution, and together they regulate a diverse set of physiologic functions. The type A1 receptors inhibit adenylyl cyclase, and play a role in the fertilization process. Animal studies also suggest a role for A1 receptors in kidney function and ethanol intoxication. Transcript variants with alternative splicing in the 5' UTR have been found for this gene.

NCBI Gene ID

134

Swiss Prot

P30542

Accession Number

P30542

Host

Rabbit

Reactivity

Human

Immunogen

This ADORA1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 298-326 amino acids from the C-terminal region of human ADORA1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle, Immunology, Neuroscience, Signal Transduction, Growth Factors

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

37 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

ADORA1

NCBI Official Name

Adenosine receptor A1

NCBI Organism

Homo sapiens

Background Reference 01

Lane, J.R., et al. Biochem. Pharmacol. 80 (8) :1180-1189 (2010)

Background Reference 02

Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)

Background Reference 03

Wagner, A.K., et al. Epilepsy Res. 90 (3) :259-272 (2010)

Background Reference 04

Ruano, G., et al. Pharmacogenomics 11 (7) :959-971 (2010)

Other Product Names

Adenosine receptor A1, ADORA1

Tested Applications

Protein ID

231473

Physical Properties

Liquid

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