GNAI2 Antibody

Product Specifications

Background

The protein encoded by this gene is an alpha subunit of guanine nucleotide binding proteins (G proteins) . The encoded protein contains the guanine nucleotide binding site and is involved in the hormonal regulation of adenylate cyclase. Several transcript variants encoding different isoforms have been detected for this gene, but the full-length nature of only two are known so far.

NCBI Gene ID

2771

Swiss Prot

P04899

Accession Number

P04899

Host

Rabbit

Reactivity

Human

Immunogen

This GNAI2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 78-107 amino acids from the N-terminal region of human GNAI2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Monkey

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

40 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

GNAI2

NCBI Official Name

Guanine nucleotide-binding protein G (i) subunit alpha-2

NCBI Organism

Homo sapiens

Background Reference 01

Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)

Background Reference 02

So, H.C., et al. Am. J. Med. Genet.Neuropsychiatr. Genet. 153B (1), 103-113 (2010) :

Background Reference 03

Talmud, P.J., et al. Am. J. Hum. Genet. 85 (5) :628-642 (2009)

Background Reference 04

Kuszak, A.J., et al. J. Biol. Chem. 284 (39) :26732-26741 (2009)

Other Product Names

Guanine nucleotide-binding protein G (i) subunit alpha-2, Adenylate cyclase-inhibiting G alpha protein, GNAI2, GNAI2B

Tested Applications

Protein ID

121023

Physical Properties

Liquid

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