EIF4ENIF1 Antibody

Product Specifications

Background

The protein encoded by this gene is a nucleocytoplasmic shuttle protein for the translation initiation factor eIF4E. This shuttle protein interacts with the importin alpha-beta complex to mediate nuclear import of eIF4E. It is predominantly cytoplasmic; its own nuclear import is regulated by a nuclear localization signal and nuclear export signals. Multiple transcript variants encoding different isoforms have been found for this gene.

NCBI Gene ID

56478

Swiss Prot

Q9NRA8

Accession Number

Q9NRA8

Host

Rabbit

Reactivity

Human

Immunogen

This EIF4ENIF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 80-108 amino acids from the N-terminal region of human EIF4ENIF1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

108 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

EIF4ENIF1

NCBI Official Name

Eukaryotic translation initiation factor 4E transporter

NCBI Organism

Homo sapiens

Background Reference 01

Suzuki, Y., et al. J. Biol. Chem. 284 (51) :35597-35604 (2009)

Background Reference 02

Venkatesan, K., et al. Nat. Methods 6 (1) :83-90 (2009)

Background Reference 03

Lee, H.C., et al. Biochem. Biophys. Res. Commun. 369 (4) :1160-1165 (2008)

Background Reference 04

Denoeud, F., et al. Genome Res. 17 (6) :746-759 (2007)

Other Product Names

Eukaryotic translation initiation factor 4E transporter, 4E-T, eIF4E transporter, Eukaryotic translation initiation factor 4E nuclear import factor 1, EIF4ENIF1