ARIH2 Antibody

Product Specifications

Background

E3 ubiquitin-protein ligase mediating 'Lys-48'-and 'Lys-63'-linked polyubiquitination and subsequent proteasomal degradation of modified proteins. May play a role in myelopoiesis.

NCBI Gene ID

10425

Swiss Prot

O95376

Accession Number

O95376

Host

Rabbit

Reactivity

Human

Immunogen

This ARIH2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 445-474 amino acids from the C-terminal region of human ARIH2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

58 kDa

Fragment

Rabbit Ig

Symbol

ARIH2

NCBI Official Name

E3 ubiquitin-protein ligase ARIH2

NCBI Organism

Homo sapiens

Background Reference 01

Marteijn, J.A., et al. Leukemia 23 (8) :1480-1489 (2009)

Background Reference 02

Marteijn, J.A., et al. Blood 110 (9) :3128-3135 (2007)

Background Reference 03

Matsuoka, S., et al. Science 316 (5828) :1160-1166 (2007)

Background Reference 04

Marteijn, J.A., et al. Blood 106 (13) :4114-4123 (2005)

Other Product Names

E3 ubiquitin-protein ligase ARIH2, ARI-2, Protein ariadne-2 homolog, 632-, Triad1 protein, ARIH2, ARI2, TRIAD1

Tested Applications

WB, IHC-P

Physical Properties

Liquid

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