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RPL8 Antibody

Product Specifications

Background

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L2P family of ribosomal proteins. It is located in the cytoplasm. In rat, the protein associates with the 5.8S rRNA, very likely participates in the binding of aminoacyl-tRNA, and is a constituent of the elongation factor 2-binding site at the ribosomal subunit interface. Alternatively spliced transcript variants encoding the same protein exist. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq].

NCBI Gene ID

6132

Swiss Prot

P62917

Accession Number

P62917

Host

Rabbit

Reactivity

Human

Immunogen

This RPL8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 207-236 amino acids from the C-terminal region of human RPL8.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine, Zebrafish, Mouse, Rat, Xenopus

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

28 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

RPL8

NCBI Official Name

60S ribosomal protein L8

NCBI Organism

Homo sapiens

Background Reference 01

Salas, S., et al. Int. J. Cancer 125 (4) :851-860 (2009)

Background Reference 02

Stelzl, U., et al. Cell 122 (6) :957-968 (2005)

Background Reference 03

Andersen, J.S., et al. Nature 433 (7021) :77-83 (2005)

Background Reference 04

Rush, J., et al. Nat. Biotechnol. 23 (1) :94-101 (2005)

Other Product Names

60S ribosomal protein L8, RPL8

Tested Applications

WB

Protein ID

51702823

Physical Properties

Liquid

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