FRAT1 Antibody
Product Specifications
Background
FRAT1 belongs to the GSK-3-binding protein family. It may function in tumor progression and in lymphomagenesis. It positively regulates the Wnt signaling pathway by stabilizing beta-catenin through the association with GSK-3. It may play a role in tumor progression and collaborate with PIM1 and MYC in lymphomagenesis.
NCBI Gene ID
10023
Swiss Prot
Q92837
Accession Number
Q92837
Host
Rabbit
Reactivity
Human
Immunogen
This FRAT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 99-128 amino acids from the Central region of human FRAT1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Immunology, Signal Transduction
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
29 kDa
Fragment
Rabbit Ig
Symbol
FRAT1
NCBI Official Name
Proto-oncogene FRAT1
NCBI Organism
Homo sapiens
Background Reference 01
Hagen, T., J. Biol. Chem. 281 (46), 35021-35029 (2006)
Background Reference 02
Wang, Y., Br. J. Cancer 94 (5), 686-691 (2006)
Background Reference 03
Hino, S., J. Biol. Chem. 278 (16), 14066-14073 (2003)
Other Product Names
Proto-oncogene FRAT1, Frequently rearranged in advanced T-cell lymphomas 1, FRAT-1, FRAT1
Tested Applications
WB, IHC-P
Protein ID
51338813
Physical Properties
Liquid
Curated Selection
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