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TAC3 Antibody

Product Specifications

Background

This gene encodes a member of the tachykinin family of secreted neuropeptides. The encoded protein is primarily expressed in the central and peripheral nervous system and functions as a neurotransmitter. This protein is the ligand for the neurokinin-3 receptor. This protein is also expressed in the outer syncytiotrophoblast of the placenta and may be associated with pregnancy-induced hypertension and pre-eclampsia. Mutations in this gene are associated with normosmic hypogonadotropic hypogonadism. Alternate splicing results in multiple transcript variants.

NCBI Gene ID

6866

Swiss Prot

Q9UHF0

Accession Number

Q9UHF0

Host

Rabbit

Reactivity

Human

Immunogen

This TAC3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 54-83 amino acids from the Central region of human TAC3.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

13 kDa

Fragment

Rabbit Ig

Symbol

TAC3

NCBI Official Name

Tachykinin-3

NCBI Organism

Homo sapiens

Background Reference 01

Klassert, T.E., et al. J. Neuroimmunol. 227 (1-2), 202-207 (2010) :

Background Reference 02

Hrabovszky, E., et al. Eur. J. Neurosci. 31 (11) :1984-1998 (2010)

Background Reference 03

Gianetti, E., et al. J. Clin. Endocrinol. Metab. 95 (6) :2857-2867 (2010)

Background Reference 04

Young, J., et al. J. Clin. Endocrinol. Metab. 95 (5) :2287-2295 (2010)

Other Product Names

Tachykinin-3, ZNEUROK1, Neurokinin-B, NKB, Neuromedin-K, TAC3, NKNB

Tested Applications

WB, IHC-P

Protein ID

18203501

Physical Properties

Liquid

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