XRN2 Antibody

Product Specifications

Background

This gene shares similarity with the mouse Dhm1 and the yeast dhp1 gene. The yeast gene is involved in homologous recombination and RNA metabolism, such as RNA synthesis and RNA trafficking. Complementation studies show that Dhm1 has a similar function in mouse as dhp1. The function of the human gene has not yet been determined. Transcript variants encoding different isoforms have been noted for this gene; however, their full-length nature is not known.

NCBI Gene ID

22803

Swiss Prot

Q9H0D6

Accession Number

Q9H0D6

Host

Rabbit

Reactivity

Human

Immunogen

This XRN2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 48-76 amino acids from the N-terminal region of human XRN2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Chicken, Drosophila, Mouse

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

109 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

XRN2

NCBI Official Name

5'-3' exoribonuclease 2

NCBI Organism

Homo sapiens

Background Reference 01

Lu, Y., et al. Oncogene 29 (7) :1041-1049 (2010)

Background Reference 02

Yang, X.C., et al. Mol. Cell. Biol. 29 (1) :31-42 (2009)

Background Reference 03

Kaneko, S., et al. Genes Dev. 21 (14) :1779-1789 (2007)

Background Reference 04

Sugiyama, N., et al. Mol. Cell Proteomics 6 (6) :1103-1109 (2007)

Other Product Names

5'-3' exoribonuclease 2, 3113-, DHM1-like protein, DHP protein, XRN2

Tested Applications

Protein ID

30173484

Physical Properties

Liquid

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