SF1 Antibody

Product Specifications

Background

This gene encodes a nuclear pre-mRNA splicing factor. The encoded protein specifically recognizes the intron branch point sequence and is required for the early stages of spliceosome assembly. Alternate splicing results in multiple transcript variants.

NCBI Gene ID

7536

Swiss Prot

Q15637

Accession Number

Q15637

Host

Rabbit

Reactivity

Human

Immunogen

This SF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 212-241 amino acids from the Central region of human SF1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

68 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

SF1

NCBI Official Name

Splicing factor 1

NCBI Organism

Homo sapiens

Background Reference 01

Jeyabalan, J., et al. PLoS ONE (5), E10646 (2010) :

Background Reference 02

Corsini, L., et al. J. Biol. Chem. 284 (1) :630-639 (2009)

Background Reference 03

Rino, J., et al. Mol. Cell. Biol. 28 (9) :3045-3057 (2008)

Background Reference 04

Olejnik-Schmidt, A.K., et al. Arch. Virol. 153 (5) :983-990 (2008)

Other Product Names

Splicing factor 1, Mammalian branch point-binding protein, BBP, mBBP, Transcription factor ZFM1, Zinc finger gene in MEN1 locus, Zinc finger protein 162, SF1, ZFM1, ZNF162