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GTF2B Antibody

Product Specifications

Background

This gene encodes the general transcription factor IIB, one of the ubiquitous factors required for transcription initiation by RNA polymerase II. The protein localizes to the nucleus where it forms a complex (the DAB complex) with transcription factors IID and IIA. Transcription factor IIB serves as a bridge between IID, the factor which initially recognizes the promoter sequence, and RNA polymerase II.

NCBI Gene ID

2959

Swiss Prot

Q00403

Accession Number

Q00403

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This GTF2B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 42-71 amino acids from the N-terminal region of human GTF2B.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine, Monkey, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=57-669

Calculated Molecular Weight

35 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

GTF2B

NCBI Official Name

Transcription initiation factor IIB

NCBI Organism

Homo sapiens

Background Reference 01

Wang, Y., et al. Curr. Biol. 20 (6) :548-553 (2010)

Background Reference 02

Thompson, N.E., et al. J. Biol. Chem. 284 (37) :24754-24766 (2009)

Background Reference 03

Gilman, B., et al. J. Biol. Chem. 284 (14) :9093-9098 (2009)

Background Reference 04

Vogt, C., et al. J. Virol. 82 (22) :11446-11453 (2008)

Other Product Names

Transcription initiation factor IIB, General transcription factor TFIIB, S300-II, GTF2B, TF2B, TFIIB

Tested Applications

WB

Protein ID

135629

Physical Properties

Liquid

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