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Desmin Antibody

Product Specifications

Background

This gene encodes a muscle-specific class III intermediate filament. Homopolymers of this protein form a stable intracytoplasmic filamentous network connecting myofibrils to each other and to the plasma membrane. Mutations in this gene are associated with desmin-related myopathy, a familial cardiac and skeletal myopathy (CSM), and with distal myopathies. [provided by RefSeq].

NCBI Gene ID

1674

Swiss Prot

P17661

Accession Number

P17661

Host

Rabbit

Reactivity

Human

Immunogen

This Desmin antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 332-359 amino acids from the C-terminal region of human Desmin.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Pig, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=57-618

Calculated Molecular Weight

54 kDa

Fragment

Rabbit Ig

Symbol

DES

NCBI Official Name

Desmin

NCBI Organism

Homo sapiens

Background Reference 01

Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)

Background Reference 02

Van Spaendonck-Zwarts, K., et al. Clin. Genet. (2010) In press :

Background Reference 03

Zimmerman, R.S., et al. Genet. Med. 12 (5) :268-278 (2010)

Background Reference 04

Bar, H., et al. J. Mol. Biol. 397 (5) :1188-1198 (2010)

Other Product Names

Desmin, DES

Tested Applications

WB, IHC-P

Protein ID

6686280

Physical Properties

Liquid

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