Desmin Antibody
Product Specifications
Background
This gene encodes a muscle-specific class III intermediate filament. Homopolymers of this protein form a stable intracytoplasmic filamentous network connecting myofibrils to each other and to the plasma membrane. Mutations in this gene are associated with desmin-related myopathy, a familial cardiac and skeletal myopathy (CSM), and with distal myopathies. [provided by RefSeq].
NCBI Gene ID
1674
Swiss Prot
P17661
Accession Number
P17661
Host
Rabbit
Reactivity
Human
Immunogen
This Desmin antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 332-359 amino acids from the C-terminal region of human Desmin.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Pig, Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
54 kDa
Fragment
Rabbit Ig
Symbol
DES
NCBI Official Name
Desmin
NCBI Organism
Homo sapiens
Background Reference 01
Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)
Background Reference 02
Van Spaendonck-Zwarts, K., et al. Clin. Genet. (2010) In press :
Background Reference 03
Zimmerman, R.S., et al. Genet. Med. 12 (5) :268-278 (2010)
Background Reference 04
Bar, H., et al. J. Mol. Biol. 397 (5) :1188-1198 (2010)
Other Product Names
Desmin, DES
Tested Applications
WB, IHC-P
Protein ID
6686280
Physical Properties
Liquid
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