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Mouse Raf1 Antibody

Product Specifications

Background

Involved in the transduction of mitogenic signals from the cell membrane to the nucleus. Part of the Ras-dependent signaling pathway from receptors to the nucleus. Protects cells from apoptosis mediated by STK3 (By similarity) .

NCBI Gene ID

110157

Swiss Prot

Q99N57

Accession Number

Q99N57

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This Mouse Raf1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 86-113 amino acids from the N-terminal region of mouse Raf1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Cell Cycle, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

73 kDa

Fragment

Rabbit Ig

Symbol

Raf1

NCBI Official Name

RAF proto-oncogene serine/threonine-protein kinase

NCBI Organism

Mus musculus

Background Reference 01

Niault, T.S., et al. Carcinogenesis 31 (7) :1165-1174 (2010)

Background Reference 02

Batarseh, A., et al. Biochemistry 49 (23) :4766-4778 (2010)

Background Reference 03

Tarutani, M., et al. J. Dermatol. Sci. 58 (1) :28-35 (2010)

Background Reference 04

Heidorn, S.J., et al. Cell 140 (2) :209-221 (2010)

Other Product Names

RAF proto-oncogene serine/threonine-protein kinase, Proto-oncogene c-RAF, cRaf, Raf-1, Raf1, Craf

Tested Applications

WB, IHC-P, Flow

Physical Properties

Liquid

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