Mouse Matk Antibody

Product Specifications

Background

Could play a significant role in the signal transduction of hematopoietic cells. May regulate tyrosine kinase activity of SRC-family members in brain by specifically phosphorylating their C-terminal regulatory tyrosine residue which acts as a negative regulatory site. It may play an inhibitory role in the control of T-cell proliferation.

NCBI Gene ID

17179

Swiss Prot

P41242

Accession Number

P41242

Host

Rabbit

Reactivity

Mouse

Immunogen

This Mouse Matk antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 477-505 amino acids from the C-terminal region of mouse Matk.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

56 kDa

Fragment

Rabbit Ig

Symbol

Matk

NCBI Official Name

Megakaryocyte-associated tyrosine-protein kinase

NCBI Organism

Mus musculus

Background Reference 01

Lee, B.C., et al. Blood 108 (3) :904-907 (2006)

Background Reference 02

Robinson, D.R., et al. Oncogene 19 (49) :5548-5557 (2000)

Background Reference 03

Puttagunta, R., et al. Genome Res. 10 (9) :1369-1380 (2000)

Background Reference 04

Samokhvalov, I., et al. Biochem. Mol. Biol. Int. 43 (1) :115-122 (1997)

Other Product Names

Megakaryocyte-associated tyrosine-protein kinase, Protein kinase NTK, Tyrosine-protein kinase CTK, Matk, Ctk, Ntk

Tested Applications

WB, IHC-P

Physical Properties

Liquid

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