Mouse Jak3 Antibody
Product Specifications
Background
Tyrosine kinase of the non-receptor type, involved in the interleukin-2 and interleukin-4 signaling pathway. Phosphorylates STAT6, IRS1, IRS2 and PI3K.
NCBI Gene ID
16453
Swiss Prot
Q62137
Accession Number
Q62137
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This Mouse Jak3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 133-161 amino acids from the N-terminal region of mouse Jak3.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
123 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
Jak3
NCBI Official Name
Tyrosine-protein kinase JAK3
NCBI Organism
Mus musculus
Background Reference 01
Martin, P., et al. Mol. Cell. Biol. 30 (20) :4877-4889 (2010)
Background Reference 02
Lange, C., et al. J. Neurochem. 113 (5) :1210-1220 (2010)
Background Reference 03
Shi, M., et al. J. Immunol. 183 (7) :4493-4501 (2009)
Background Reference 04
Chang, B.Y., et al. J. Immunol. 183 (3) :2183-2192 (2009)
Other Product Names
Tyrosine-protein kinase JAK3, Janus kinase 3, JAK-3, Jak3
Tested Applications
WB
Physical Properties
Liquid
Curated Selection
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