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Mouse Irak3 Antibody

Product Specifications

Background

Irak3 inhibits dissociation of IRAK1 and IRAK4 from the Toll-like receptor signaling complex by either inhibiting the phosphorylation of IRAK1 and IRAK4 or stabilizing the receptor complex.

NCBI Gene ID

73914

Swiss Prot

Q8K4B2

Accession Number

Q8K4B2

Host

Rabbit

Reactivity

Mouse

Immunogen

This Mouse Irak3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 517-544 amino acids from the C-terminal region of mouse Irak3.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Immunology, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

68 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

Irak3

NCBI Official Name

Interleukin-1 receptor-associated kinase 3

NCBI Organism

Mus musculus

Background Reference 01

Turnis, M.E., et al. J. Immunol. 185 (7) :4223-4232 (2010)

Background Reference 02

Hubbard, L.L., et al. J. Immunol. 184 (11) :6299-6308 (2010)

Background Reference 03

Seki, M., et al. J. Immunol. 184 (3) :1410-1418 (2010)

Background Reference 04

Lyn-Kew, K., et al. PLoS ONE (6), E11145 (2010) :

Other Product Names

Interleukin-1 receptor-associated kinase 3, IRAK-3, IL-1 receptor-associated kinase M, IRAK-M, Irak3 {ECO:0000312|MGI:MGI:1921164}

Tested Applications

WB

Physical Properties

Liquid

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