POLR2J Antibody
Product Specifications
Background
This gene encodes a subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene exists as a heterodimer with another polymerase subunit; together they form a core subassembly unit of the polymerase. Two similar genes are located nearby on chromosome 7q22.1 and a pseudogene is found on chromosome 7p13.
NCBI Gene ID
5439
Swiss Prot
P52435
Accession Number
P52435
Host
Rabbit
Reactivity
Human
Immunogen
This POLR2J antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 89-117 amino acids from the C-terminal region of human POLR2J.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Bovine
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
13 kDa
Fragment
Rabbit Ig
Symbol
POLR2J
NCBI Official Name
DNA-directed RNA polymerase II subunit RPB11-a
NCBI Organism
Homo sapiens
Background Reference 01
Michiels, S., et al. Carcinogenesis 30 (5) :763-768 (2009)
Background Reference 02
Oh, J.H., et al. Mamm. Genome 16 (12) :942-954 (2005)
Background Reference 03
Shpakovskii, D.G., et al. Bioorg. Khim. 30 (6) :621-625 (2004)
Background Reference 04
Zhou, M., et al. Proc. Natl. Acad. Sci. U.S.A. 100 (22) :12666-12671 (2003)
Other Product Names
DNA-directed RNA polymerase II subunit RPB11-a, RNA polymerase II subunit B11-a, RPB11a, DNA-directed RNA polymerase II subunit J-1, RNA polymerase II 133 kDa subunit, POLR2J, POLR2J1
Tested Applications
WB, IHC-P
Physical Properties
Liquid
Frequently Asked Questions
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