POLR2J Antibody

Product Specifications

Background

This gene encodes a subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene exists as a heterodimer with another polymerase subunit; together they form a core subassembly unit of the polymerase. Two similar genes are located nearby on chromosome 7q22.1 and a pseudogene is found on chromosome 7p13.

NCBI Gene ID

5439

Swiss Prot

P52435

Accession Number

P52435

Host

Rabbit

Reactivity

Human

Immunogen

This POLR2J antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 89-117 amino acids from the C-terminal region of human POLR2J.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

13 kDa

Fragment

Rabbit Ig

Symbol

POLR2J

NCBI Official Name

DNA-directed RNA polymerase II subunit RPB11-a

NCBI Organism

Homo sapiens

Background Reference 01

Michiels, S., et al. Carcinogenesis 30 (5) :763-768 (2009)

Background Reference 02

Oh, J.H., et al. Mamm. Genome 16 (12) :942-954 (2005)

Background Reference 03

Shpakovskii, D.G., et al. Bioorg. Khim. 30 (6) :621-625 (2004)

Background Reference 04

Zhou, M., et al. Proc. Natl. Acad. Sci. U.S.A. 100 (22) :12666-12671 (2003)

Other Product Names

DNA-directed RNA polymerase II subunit RPB11-a, RNA polymerase II subunit B11-a, RPB11a, DNA-directed RNA polymerase II subunit J-1, RNA polymerase II 133 kDa subunit, POLR2J, POLR2J1