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KCNK10 Antibody

Product Specifications

Background

The protein encoded by this gene belongs to the family of potassium channel proteins containing two pore-forming P domains. This channel is an open rectifier which primarily passes outward current under physiological K+ concentrations, and is stimulated strongly by arachidonic acid and to a lesser degree by membrane stretching, intracellular acidification, and general anaesthetics. Several alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq].

NCBI Gene ID

54207

Swiss Prot

P57789

Accession Number

P57789

Host

Rabbit

Reactivity

Human

Immunogen

This KCNK10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 504-532 amino acids from the C-terminal region of human KCNK10.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=57-588

Calculated Molecular Weight

60 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

KCNK10

NCBI Official Name

Potassium channel subfamily K member 10

NCBI Organism

Homo sapiens

Background Reference 01

Gierten, J., et al. Br. J. Pharmacol. 154 (8) :1680-1690 (2008)

Background Reference 02

Huang, D., et al. Med. Hypotheses 70 (3) :618-624 (2008)

Background Reference 03

Goldstein, S.A., et al. Pharmacol. Rev. 57 (4) :527-540 (2005)

Background Reference 04

Gu, W., et al. J. Physiol. (Lond.) 539 (PT 3), 657-668 (2002) :

Other Product Names

Potassium channel subfamily K member 10, Outward rectifying potassium channel protein TREK-2, TREK-2 K (+) channel subunit, KCNK10, TREK2

Tested Applications

WB

Protein ID

13431412

Physical Properties

Liquid

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