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CCL15 Antibody

Product Specifications

Background

This gene, chemokine (C-C motif) ligand 15, is one of several CC cytokine genes clustered on 17q11.2. The CC cytokines are secreted proteins characterized by two adjacent cysteines. The cytokine encoded by this gene is chemotactic for T cells and monocytes and induces N-acetyl-beta-D-glucosaminidase release in monocytes. It induces changes in intracellular calcium concentration in monocytes and is thought to act through the CCR1 receptor. Read-through transcripts are expressed that include exons from the downstream cytokine gene, chemokine (C-C motif) ligand 14, and are represented as GeneID: 348249.

NCBI Gene ID

6359

Swiss Prot

Q16663

Accession Number

Q16663

Host

Rabbit

Reactivity

Human

Immunogen

This CCL15 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 71-100 amino acids from the C-terminal region of human CCL15.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Immunology

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

12 kDa

Fragment

Rabbit Ig

Symbol

CCL15

NCBI Official Name

C-C motif chemokine 15

NCBI Organism

Homo sapiens

Background Reference 01

Kitamura, T., et al. Proc. Natl. Acad. Sci. U.S.A. 107 (29) :13063-13068 (2010)

Background Reference 02

Cho, J.E., et al. Mol. Cells 29 (1) :35-39 (2010)

Background Reference 03

Kwon, S.H., et al. Nutr Res Pract 2 (2) :134-137 (2008)

Background Reference 04

Zhang, Z., et al. Protein Sci. 13 (10) :2819-2824 (2004)

Other Product Names

C-C motif chemokine 15, Chemokine CC-2, HCC-2, Leukotactin-1, LKN-1, MIP-1 delta, Macrophage inflammatory protein 5, MIP-5, Mrp-2b, NCC-3, Small-inducible cytokine A15, CCL15 (22-92), CCL15 (25-92), CCL15 (29-92), CCL15, MIP5, NCC3, SCYA15

Tested Applications

WB, IHC-P

Protein ID

3915594

Physical Properties

Liquid

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