NPFFR1 Antibody

Product Specifications

Background

Receptor for NPAF (A-18-F-amide) and NPFF (F-8-F-amide) neuropeptides, also known as morphine-modulating peptides. Can also be activated by a variety of naturally occurring or synthetic FMRF-amide like ligands. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.

NCBI Gene ID

64106

Swiss Prot

Q9GZQ6

Accession Number

Q9GZQ6

Host

Rabbit

Reactivity

Human

Immunogen

This NPFFR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 337-366 amino acids from the C-terminal region of human NPFFR1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience, Signal Transduction, Growth Factors

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

48 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

NPFFR1

NCBI Official Name

Neuropeptide FF receptor 1

NCBI Organism

Homo sapiens

Background Reference 01

Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :

Background Reference 02

Ubuka, T., et al. PLoS ONE (12), E8400 (2009) :

Background Reference 03

Dowal, L., et al. J. Biol. Chem. 281 (33) :23999-24014 (2006)

Background Reference 04

Grupe, A., et al. Am. J. Hum. Genet. 78 (1) :78-88 (2006)

Other Product Names

Neuropeptide FF receptor 1, G-protein coupled receptor 147, RFamide-related peptide receptor OT7T022, NPFFR1, GPR147, NPFF1

Tested Applications

Protein ID

13878599

Physical Properties

Liquid

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