HDC Antibody
Product Specifications
Background
This gene encodes a member of the group II decarboxylase family and forms a homodimer that converts L-histidine to histamine in a pyridoxal phosphate dependent manner. Histamine regulates several physiologic processes, including neurotransmission, gastric acid secretion, inflamation, and smooth muscle tone.
NCBI Gene ID
3067
Swiss Prot
P19113
Accession Number
P19113
Host
Rabbit
Reactivity
Human
Immunogen
This HDC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 147-178 amino acids from the N-terminal region of human HDC.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Obesity, Neuroscience, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
74 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
HDC
NCBI Official Name
Histidine decarboxylase
NCBI Organism
Homo sapiens
Background Reference 01
Gervasini, G., et al. Allergy (2010) In press :
Background Reference 02
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Background Reference 03
Ercan-Sencicek, A.G., et al. N. Engl. J. Med. 362 (20) :1901-1908 (2010)
Background Reference 04
Jeong, H.J., et al. Cell. Mol. Life Sci. 66 (7) :1309-1319 (2009)
Other Product Names
Histidine decarboxylase, HDC, HDC
Tested Applications
WB
Protein ID
1352220
Physical Properties
Liquid
Curated Selection
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