MLL5 Antibody

Product Specifications

Background

This gene is a member of the myeloid/lymphoid or mixed-lineage leukemia (MLL) family and encodes a protein with an N-terminal PHD zinc finger and a central SET domain. Overexpression of the protein inhibits cell cycle progression. Alternate transcriptional splice variants have been characterized. [provided by RefSeq].

NCBI Gene ID

55904

Swiss Prot

Q8IZD2

Accession Number

Q8IZD2

Host

Rabbit

Reactivity

Human

Immunogen

This MLL5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 93-120 amino acids from the N-terminal region of human MLL5.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Cell Cycle, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

205 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

KMT2E

NCBI Official Name

Histone-lysine N-methyltransferase 2E

NCBI Organism

Homo sapiens

Background Reference 01

Liu, J., et al. J. Biol. Chem. 285 (27) :20904-20914 (2010)

Background Reference 02

Fujiki, R., et al. Nature 459 (7245) :455-459 (2009)

Background Reference 03

Cheng, F., et al. Int. J. Biochem. Cell Biol. 40 (11) :2472-2481 (2008)

Background Reference 04

Sun, X.J., et al. PLoS ONE (1), E1499 (2008) :

Other Product Names

Histone-lysine N-methyltransferase 2E, Lysine N-methyltransferase 2E, Myeloid/lymphoid or mixed-lineage leukemia protein 5, KMT2E, MLL5

Tested Applications

Protein ID

74723669

Physical Properties

Liquid

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