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COL3A1 Antibody

Product Specifications

Background

This gene encodes the pro-alpha1 chains of type III collagen, a fibrillar collagen that is found in extensible connective tissues such as skin, lung, uterus, intestine and the vascular system, frequently in association with type I collagen. Mutations in this gene are associated with Ehlers-Danlos syndrome types IV, and with aortic and arterial aneurysms. Two transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene. [provided by R. Dalgleish].

NCBI Gene ID

1281

Swiss Prot

P02461

Accession Number

P02461

Host

Rabbit

Reactivity

Human

Immunogen

This COL3A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1410-1438 amino acids from the C-terminal region of human COL3A1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

139 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

COL3A1

NCBI Official Name

Collagen alpha-1 (III) chain

NCBI Organism

Homo sapiens

Background Reference 01

Romero, R., et al. Am. J. Obstet. Gynecol. 203 (4), 361 (2010) :

Background Reference 02

Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)

Background Reference 03

Romero, R., et al. Am. J. Obstet. Gynecol. 202 (5), 431 (2010) :

Background Reference 04

Taddese, S., et al. Biochim. Biophys. Acta 1804 (4) :731-739 (2010)

Other Product Names

Collagen alpha-1 (III) chain, COL3A1

Tested Applications

WB

Protein ID

124056490

Physical Properties

Liquid

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